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Force-specific activation of Smad1/5 regulates vascular endothelial cell cycle progression in response to disturbed flow
Vascular endothelial cells (ECs) are constantly exposed to blood flow-induced shear stress, but the mechanism of force-specific activation of their signaling to modulate cellular function remains unclear. We have demonstrated that bone morphogenetic protein receptor (BMPR)-specific Smad1/5 can be fo...
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| Główni autorzy: | , , , , , , , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
National Academy of Sciences
2012
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3356658/ https://ncbi.nlm.nih.gov/pubmed/22550179 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1205476109 |
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