Kidney Proximal Tubule Lipoapoptosis Is Regulated by Fatty Acid Transporter-2 (FATP2)

Albuminuria and tubular atrophy are among the highest risks for CKD progression to ESRD. A parsimonious mechanism involves leakage of albumin-bound nonesterified fatty acids (NEFAs) across the damaged glomerular filtration barrier and subsequent reabsorption by the downstream proximal tubule, causin...

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Detalhes bibliográficos
Publicado no:J Am Soc Nephrol
Main Authors: Khan, Shenaz, Cabral, Pablo D., Schilling, William P., Schmidt, Zachary W., Uddin, Asif N., Gingras, Amelia, Madhavan, Sethu M., Garvin, Jeffrey L., Schelling, Jeffrey R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2018
Assuntos:
Basic Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5748912/
https://ncbi.nlm.nih.gov/pubmed/28993506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2017030314
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