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Chemical basis for deuterium labeling of fat and NADPH

Much understanding of metabolism is based on monitoring chemical reactions in cells with isotope tracers. For this purpose, (13)C is well suited due to its stable incorporation into bio-molecules and minimal kinetic isotope effect. For redox reactions, however, deuterium tracing can provide valuable...

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Bibliographische Detailangaben
Veröffentlicht in:J Am Chem Soc
Hauptverfasser: Zhang, Zhaoyue, Chen, Li, Liu, Ling, Su, Xiaoyang, Rabinowitz, Joshua. D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5748894/
https://ncbi.nlm.nih.gov/pubmed/28911221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.7b08012
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