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Luciferase-based reporter to monitor the transcriptional activity of the SIRT3 promoter
Sirtuin 3 (SIRT3) is a major regulator of oncometabolism. Its activity or lack thereof significantly affects cellular oxidative stress, glycolytic gene expression, and tumorigenic potential. Thus, a system to accurately measure the level of SIRT3 transcriptional activation could lead to the identifi...
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| 發表在: | Methods Enzymol |
|---|---|
| Main Authors: | , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2014
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5748892/ https://ncbi.nlm.nih.gov/pubmed/24924131 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/B978-0-12-801329-8.00007-6 |
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