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Mitochondria and α-Synuclein: Friends or Foes in the Pathogenesis of Parkinson’s Disease?

Parkinson’s disease (PD) is a movement disorder characterized by dopaminergic nigrostriatal neuron degeneration and the formation of Lewy bodies (LB), pathological inclusions containing fibrils that are mainly composed of α-synuclein. Dopaminergic neurons, for their intrinsic characteristics, have a...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Genes (Basel)
Hauptverfasser: Faustini, Gaia, Bono, Federica, Valerio, Alessandra, Pizzi, Marina, Spano, PierFranco, Bellucci, Arianna
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5748695/
https://ncbi.nlm.nih.gov/pubmed/29292725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes8120377
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