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Orexin Receptor Multimerization versus Functional Interactions: Neuropharmacological Implications for Opioid and Cannabinoid Signalling and Pharmacogenetics
Orexins/hypocretins are neuropeptides formed by proteolytic cleavage of a precursor peptide, which are produced by neurons found in the lateral hypothalamus. The G protein-coupled receptors (GPCRs) for these ligands, the OX(1) and OX(2) orexin receptors, are more widely expressed throughout the cent...
שמור ב:
| הוצא לאור ב: | Pharmaceuticals (Basel) |
|---|---|
| Main Authors: | , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
MDPI
2017
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5748636/ https://ncbi.nlm.nih.gov/pubmed/28991183 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph10040079 |
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