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Immortalized Muscle Cell Model to Test the Exon Skipping Efficacy for Duchenne Muscular Dystrophy

Duchenne muscular dystrophy (DMD) is a lethal genetic disorder that most commonly results from mutations disrupting the reading frame of the dystrophin (DMD) gene. Among the therapeutic approaches employed, exon skipping using antisense oligonucleotides (AOs) is one of the most promising strategies....

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Bibliografische gegevens
Gepubliceerd in:J Pers Med
Hoofdauteurs: Nguyen, Quynh, Yokota, Toshifumi
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: MDPI 2017
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5748625/
https://ncbi.nlm.nih.gov/pubmed/29035327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jpm7040013
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