Targeting the lipid metabolic axis ACSL/SCD in colorectal cancer progression by therapeutic miRNAs: miR-19b-1 role

An abnormal acyl-CoA synthetase/stearoyl-CoA desaturase (ACSL/SCD) lipid network fuels colon cancer progression, endowing cells with invasive and migratory properties. Therapies against this metabolic network may be useful to improve clinical outcomes. Because micro-RNAs (miRNAs/miRs) are important...

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Detalles Bibliográficos
Publicado en:J Lipid Res
Autores principales: Cruz-Gil, Silvia, Sanchez-Martinez, Ruth, Gomez de Cedron, Marta, Martin-Hernandez, Roberto, Vargas, Teodoro, Molina, Susana, Herranz, Jesús, Davalos, Alberto, Reglero, Guillermo, Ramirez de Molina, Ana
Formato: Artigo
Lenguaje:Inglês
Publicado: The American Society for Biochemistry and Molecular Biology 2018
Materias:
Research Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5748493/
https://ncbi.nlm.nih.gov/pubmed/29074607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M076752
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