Estrogen receptor mutations and splice variants determined in liquid biopsies from metastatic breast cancer patients

Mutations and splice variants in the estrogen receptor (ER) gene, ESR1, may yield endocrine resistance in metastatic breast cancer (MBC) patients. These putative endocrine resistance markers are likely to emerge during treatment, and therefore, its detection in liquid biopsies, such as circulating t...

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Publicat a:Mol Oncol
Autors principals: Beije, Nick, Sieuwerts, Anieta M., Kraan, Jaco, Van, Ngoc M., Onstenk, Wendy, Vitale, Silvia R., van der Vlugt‐Daane, Michelle, Dirix, Luc Y., Brouwer, Anja, Hamberg, Paul, de Jongh, Felix E., Jager, Agnes, Seynaeve, Caroline M., Jansen, Maurice P. H. M., Foekens, John A., Martens, John W. M., Sleijfer, Stefan
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2017
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5748489/
https://ncbi.nlm.nih.gov/pubmed/29063679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1878-0261.12147
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