Estrogen receptor mutations and splice variants determined in liquid biopsies from metastatic breast cancer patients

Mutations and splice variants in the estrogen receptor (ER) gene, ESR1, may yield endocrine resistance in metastatic breast cancer (MBC) patients. These putative endocrine resistance markers are likely to emerge during treatment, and therefore, its detection in liquid biopsies, such as circulating t...

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Publicado en:Mol Oncol
Autores principales: Beije, Nick, Sieuwerts, Anieta M., Kraan, Jaco, Van, Ngoc M., Onstenk, Wendy, Vitale, Silvia R., van der Vlugt‐Daane, Michelle, Dirix, Luc Y., Brouwer, Anja, Hamberg, Paul, de Jongh, Felix E., Jager, Agnes, Seynaeve, Caroline M., Jansen, Maurice P. H. M., Foekens, John A., Martens, John W. M., Sleijfer, Stefan
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley and Sons Inc. 2017
Materias:
Research Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5748489/
https://ncbi.nlm.nih.gov/pubmed/29063679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1878-0261.12147
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