X‐linked inhibitor of apoptosis inhibition sensitizes acute myeloid leukemia cell response to TRAIL and chemotherapy through potentiated induction of proapoptotic machinery

Acute myeloid leukemia (AML) is an aggressive disease with an increasing incidence and relatively low 5‐year survival rate. Unfortunately, the underlying mechanism of leukemogenesis is poorly known, and there has been little progress in the treatment for AML. Studies have shown that X‐linked inhibit...

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Bibliografiske detaljer
Udgivet i:Mol Oncol
Main Authors: Zhou, Jianbiao, Lu, Xiao, Tan, Tuan Zea, Chng, Wee‐Joo
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2017
Fag:
Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5748481/
https://ncbi.nlm.nih.gov/pubmed/29063676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1878-0261.12146
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