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Creation of Stable Heterothallic Strains of Komagataella phaffii Enables Dissection of Mating Gene Regulation

The methylotrophic yeast Komagataella phaffii (Pichia pastoris) is homothallic and has been reported to switch mating type by an ancient inversion mechanism. Two mating-type (MAT) loci include homologs of the MATa and MATα transcription factor genes, with the expression from one locus downregulated...

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Detalhes bibliográficos
Publicado no:Mol Cell Biol
Main Authors: Heistinger, Lina, Gasser, Brigitte, Mattanovich, Diethard
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5748462/
https://ncbi.nlm.nih.gov/pubmed/29061733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00398-17
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