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Creation of Stable Heterothallic Strains of Komagataella phaffii Enables Dissection of Mating Gene Regulation

The methylotrophic yeast Komagataella phaffii (Pichia pastoris) is homothallic and has been reported to switch mating type by an ancient inversion mechanism. Two mating-type (MAT) loci include homologs of the MATa and MATα transcription factor genes, with the expression from one locus downregulated...

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Bibliografiska uppgifter
I publikationen:Mol Cell Biol
Huvudupphovsmän: Heistinger, Lina, Gasser, Brigitte, Mattanovich, Diethard
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2017
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5748462/
https://ncbi.nlm.nih.gov/pubmed/29061733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00398-17
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