ATG-dependent phagocytosis in dendritic cells drives myelin-specific CD4(+) T cell pathogenicity during CNS inflammation

Although reactivation and accumulation of autoreactive CD4(+) T cells within the CNS are considered to play a key role in the pathogenesis of multiple sclerosis (MS) and its animal model, experimental autoimmune encephalomyelitis (EAE), the mechanisms of how these cells recognize their target organ...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Keller, Christian W., Sina, Christina, Kotur, Monika B., Ramelli, Giulia, Mundt, Sarah, Quast, Isaak, Ligeon, Laure-Anne, Weber, Patrick, Becher, Burkhard, Münz, Christian, Lünemann, Jan D.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2017
Assuntos:
PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5748192/
https://ncbi.nlm.nih.gov/pubmed/29233943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1713664114
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados