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Biochemical and Functional Evaluation of the Intramolecular Disulfide Bonds in the Zinc-Chelating Antimicrobial Protein Human S100A7 (Psoriasin)

Human S100A7 (psoriasin) is a metal-chelating protein expressed by epithelial cells. It is a 22-kDa homodimer with two EF-hand domains per subunit, and two transition-metal-binding His(3)Asp sites at the dimer interface. Each subunit contains two cysteine residues that can exist as free thiols (S100...

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Detalhes bibliográficos
Publicado no:Biochemistry
Main Authors: Cunden, Lisa S., Brophy, Megan Brunjes, Rodriguez, Grayson E., Flaxman, Hope A., Nolan, Elizabeth M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5748159/
https://ncbi.nlm.nih.gov/pubmed/28976190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.7b00781
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