Asymmetry between Activation and Deactivation during a Transcriptional Pulse

Transcription in eukaryotic cells occurs in gene-specific bursts or pulses of activity. Recent studies identified a spectrum of transcriptionally active “on-states,” interspersed with periods of inactivity, but these “off-states” and the process of transcriptional deactivation are poorly understood....

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Udgivet i:Cell Syst
Main Authors: Dunham, Lee S.S., Momiji, Hiroshi, Harper, Claire V., Downton, Polly J., Hey, Kirsty, McNamara, Anne, Featherstone, Karen, Spiller, David G., Rand, David A., Finkenstädt, Bärbel, White, Michael R.H., Davis, Julian R.E.
Format: Artigo
Sprog:Inglês
Udgivet: Cell Press 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5747351/
https://ncbi.nlm.nih.gov/pubmed/29153839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cels.2017.10.013
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