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Rlim-dependent and -independent pathways for X chromosome inactivation in female ESCs

During female mouse embryogenesis, two forms of X chromosome inactivation (XCI) ensure dosage compensation from sex chromosomes. Beginning at the four-cell stage, imprinted XCI (iXCI) exclusively silences the paternal X (Xp), and this pattern is maintained in extraembryonic cell types. Epiblast cell...

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發表在:Cell Rep
Main Authors: Wang, Feng, McCannell, Kurtis N., Bošković, Ana, Zhu, Xiaochun, Shin, JongDae, Yu, Jun, Gallant, Judith, Byron, Meg, Lawrence, Jeanne B., Zhu, Lihua J., Jones, Stephen N., Rando, Oliver J., Fazzio, Thomas G., Bach, Ingolf
格式: Artigo
語言:Inglês
出版: 2017
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5747310/
https://ncbi.nlm.nih.gov/pubmed/29281819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2017.12.004
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