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Releasing the break on X chromosome inactivation: Rnf12/RLIM targets REX1 for degradation

One of the two X chromosomes in cells of female mammals is transcriptionally silenced in a process known as X chromosome inactivation (XCI). Initiation of XCI is regulated by the ubiquitin ligase Rnf12/RLIM, but the mechanisms by which Rnf12/RLIM mediates this process has been a mystery. A recent st...

詳細記述

保存先:
書誌詳細
第一著者: Bach, Ingolf
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3494387/
https://ncbi.nlm.nih.gov/pubmed/22785560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2012.98
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