DE-kupl: exhaustive capture of biological variation in RNA-seq data through k-mer decomposition

We introduce a k-mer-based computational protocol, DE-kupl, for capturing local RNA variation in a set of RNA-seq libraries, independently of a reference genome or transcriptome. DE-kupl extracts all k-mers with differential abundance directly from the raw data files. This enables the retrieval of v...

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Bibliografiske detaljer
Udgivet i:Genome Biol
Main Authors: Audoux, Jérôme, Philippe, Nicolas, Chikhi, Rayan, Salson, Mikaël, Gallopin, Mélina, Gabriel, Marc, Le Coz, Jérémy, Drouineau, Emilie, Commes, Thérèse, Gautheret, Daniel
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2017
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5747171/
https://ncbi.nlm.nih.gov/pubmed/29284518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-017-1372-2
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