mTOR inhibition improves the immunomodulatory properties of human bone marrow mesenchymal stem cells by inducing COX-2 and PGE(2)

BACKGROUND: Bone marrow mesenchymal stem cells (MSCs) are promising candidates for the treatment of various inflammatory disorders due to their profound immunomodulatory properties. However, the immunosuppressive capacity of MSCs needs activation by an inflammatory microenvironment, which may negati...

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Detalhes bibliográficos
Publicado no:Stem Cell Res Ther
Main Authors: Wang, Binsheng, Lin, Yu, Hu, Yongxian, Shan, Wei, Liu, Senquan, Xu, Yulin, Zhang, Hao, Cai, Shuyang, Yu, Xiaohong, Cai, Zhen, Huang, He
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5747167/
https://ncbi.nlm.nih.gov/pubmed/29287601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-017-0744-6
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