Involvements of p38 MAPK and oxidative stress in the ozone-induced enhancement of AHR and pulmonary inflammation in an allergic asthma model

BACKGROUND: Exposure to ambient ozone (O(3)) increases the susceptivity to allergens and triggers exacerbations in patients with asthma. However, the detailed mechanisms of action for O(3) to trigger asthma exacerbations are still unclear. METHODS: An ovalbumin (OVA)-established asthmatic mouse mode...

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Detalhes bibliográficos
Publicado no:Respir Res
Main Authors: Bao, Aihua, Yang, Hong, Ji, Jie, Chen, Yuqin, Bao, Wuping, Li, Feng, Zhang, Min, Zhou, Xin, Li, Qiang, Ben, Suqin
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5747109/
https://ncbi.nlm.nih.gov/pubmed/29284473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12931-017-0697-4
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