PRMT5 Is a Critical Regulator of Breast Cancer Stem Cell Function via Histone Methylation and FOXP1 Expression

Breast cancer progression, treatment resistance, and relapse are thought to originate from a small population of tumor cells, breast cancer stem cells (BCSCs). Identification of factors critical for BCSC function is therefore vital for the development of therapies. Here, we identify the arginine met...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Chiang, Kelly, Zielinska, Agnieszka E., Shaaban, Abeer M., Sanchez-Bailon, Maria Pilar, Jarrold, James, Clarke, Thomas L., Zhang, Jingxian, Francis, Adele, Jones, Louise J., Smith, Sally, Barbash, Olena, Guccione, Ernesto, Farnie, Gillian, Smalley, Matthew J., Davies, Clare C.
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5746596/
https://ncbi.nlm.nih.gov/pubmed/29262329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2017.11.096
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