Strategy to detect pre-existing immunity to AAV gene therapy

Gene therapy may offer a new treatment option, particularly for patients with severe hemophilia, based on recent research. However, individuals with pre-existing immunity to adeno-associated viruses (AAVs) may be less likely to benefit from AAV vector-based therapies. To study pre-existing AAV5 immu...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Gene Ther
Prif Awduron: Falese, L, Sandza, K, Yates, B, Triffault, S, Gangar, S, Long, B, Tsuruda, L, Carter, B, Vettermann, C, Zoog, S J, Fong, S
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group 2017
Pynciau:
Original Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5746592/
https://ncbi.nlm.nih.gov/pubmed/29106404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gt.2017.95
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