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The role of astrocytes in amyloid production and Alzheimer's disease

Alzheimer's disease (AD) is marked by the presence of extracellular amyloid beta (Aβ) plaques, intracellular neurofibrillary tangles (NFTs) and gliosis, activated glial cells, in the brain. It is thought that Aβ plaques trigger NFT formation, neuronal cell death, neuroinflammation and gliosis a...

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Bibliografiske detaljer
Udgivet i:Open Biol
Main Authors: Frost, Georgia R., Li, Yue-Ming
Format: Artigo
Sprog:Inglês
Udgivet: The Royal Society 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5746550/
https://ncbi.nlm.nih.gov/pubmed/29237809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsob.170228
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