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The role of astrocytes in amyloid production and Alzheimer's disease

Alzheimer's disease (AD) is marked by the presence of extracellular amyloid beta (Aβ) plaques, intracellular neurofibrillary tangles (NFTs) and gliosis, activated glial cells, in the brain. It is thought that Aβ plaques trigger NFT formation, neuronal cell death, neuroinflammation and gliosis a...

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Detalhes bibliográficos
Publicado no:Open Biol
Main Authors: Frost, Georgia R., Li, Yue-Ming
Formato: Artigo
Idioma:Inglês
Publicado em: The Royal Society 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5746550/
https://ncbi.nlm.nih.gov/pubmed/29237809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsob.170228
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