Pro-atherogenic flow increases endothelial stiffness via enhanced CD36-mediated oxLDL uptake

OBJECTIVE: Disturbed flow (DF) is well-known to induce endothelial dysfunction and synergistically with plasma dyslipidemia facilitate plaque formation. Little is known, however, about the synergistic impact of DF and dyslipidemia on endothelial biomechanics. Our goal was to determine the impact of...

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Pubblicato in:Arterioscler Thromb Vasc Biol
Autori principali: LeMaster, Elizabeth, Huang, Ru-Ting, Zhang, Chongxu, Bogachkov, Yedida, Coles, Cassandre, Shentu, Tzu-Pin, Sheng, Yue, Fancher, Ibra S., Ng, Carlos, Christoforidis, Theodore, Subbaiah, Pappasani V., Berdyshev, Evgeny, Qain, Zhijian, Eddington, David T., Lee, James, Cho, Michael, Fang, Yun, Minshall, Richard D., Levitan, Irena
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5746473/
https://ncbi.nlm.nih.gov/pubmed/29025707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.117.309907
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