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Pro-atherogenic flow increases endothelial stiffness via enhanced CD36-mediated oxLDL uptake

OBJECTIVE: Disturbed flow (DF) is well-known to induce endothelial dysfunction and synergistically with plasma dyslipidemia facilitate plaque formation. Little is known, however, about the synergistic impact of DF and dyslipidemia on endothelial biomechanics. Our goal was to determine the impact of...

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Vydáno v:Arterioscler Thromb Vasc Biol
Hlavní autoři: LeMaster, Elizabeth, Huang, Ru-Ting, Zhang, Chongxu, Bogachkov, Yedida, Coles, Cassandre, Shentu, Tzu-Pin, Sheng, Yue, Fancher, Ibra S., Ng, Carlos, Christoforidis, Theodore, Subbaiah, Pappasani V., Berdyshev, Evgeny, Qain, Zhijian, Eddington, David T., Lee, James, Cho, Michael, Fang, Yun, Minshall, Richard D., Levitan, Irena
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5746473/
https://ncbi.nlm.nih.gov/pubmed/29025707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.117.309907
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