Učitavanje...
Sustained Activation of RhoGTPases Promotes a Synthetic Pulmonary Artery Smooth Muscle Cell Phenotype in Neprilysin Null Mice
OBJECTIVE: Pulmonary artery smooth muscle cells (PASMCs) from Neprilysin (NEP) null mice exhibit a synthetic phenotype and increased activation of RhoGTPases compared to their wild type (wt) counterparts. Although RhoGTPases are known to promote a contractile SMC phenotype, we hypothesize that their...
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| Izdano u: | Arterioscler Thromb Vasc Biol |
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| Glavni autori: | , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2017
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5746466/ https://ncbi.nlm.nih.gov/pubmed/29191928 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.117.310207 |
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