PKM2 in carcinogenesis and oncotherapy

Tumor cell metabolism is characterized by abundant glucose consumption and aerobic glycolysis. And pyruvate kinase M2 (PKM2) plays a decisive role in glycolysis, significantly contributing to the Warburg effect, tumor growth, angiogenesis, cell division, metastasis and apoptosis. To date, researcher...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:Oncotarget
Auteurs principaux: He, Xia, Du, Suya, Lei, Tiantian, Li, Xiang, Liu, Yilong, Wang, Hailian, Tong, Rongsheng, Wang, Yi
Format: Artigo
Langue:Inglês
Publié: Impact Journals LLC 2017
Sujets:
Review
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5746412/
https://ncbi.nlm.nih.gov/pubmed/29299177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.22529
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