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Mangiferin induces islet regeneration in aged mice through regulating p16(INK4a)

Previous studies by our group on mangiferin demonstrated that it exerts an antihyperglycemic effect through the regulation of cell cycle proteins in 3-month-old, partially pancreatectomized (PPx) mice. However, β-cell proliferation is known to become severely restricted with advanced age. Therefore,...

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Detalhes bibliográficos
Publicado no:Int J Mol Med
Main Authors: Wang, Hailian, He, Xia, Lei, Tiantian, Liu, Yilong, Huai, Guoli, Sun, Minghan, Deng, Shaoping, Yang, Hongji, Tong, Rongsheng, Wang, Yi
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5881804/
https://ncbi.nlm.nih.gov/pubmed/29512742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijmm.2018.3524
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