Inhibition of PI4K IIIα radiosensitizes in human tumor xenograft and immune-competent syngeneic murine tumor model

Phosphatidylinositol (PI) 4-kinase (PI4K) has emerged as a potential target for anti-cancer treatment. We recently reported that simeprevir, an anti-hepatitis C viral (HCV) agent, radiosensitized diverse human cancer cells by inhibiting PI4K IIIα in vitro. In this study, we investigated the radiosen...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Park, Younghee, Park, Ji Min, Kim, Dan Hyo, Kwon, Jeanny, Kim, In Ah
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5746391/
https://ncbi.nlm.nih.gov/pubmed/29299156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.22778
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