Radiosensitization with combined use of olaparib and PI-103 in triple-negative breast cancer

BACKGROUND: Triple-negative breast cancer (TNBC) shows aggressive clinical behavior, but the treatment options are limited due to lack of a specific target. TNBC shares many clinical and pathological similarities with BRCA-deficient breast cancer, for which poly(ADP-ribose) polymerase (PARP) inhibit...

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Veröffentlicht in:BMC Cancer
Hauptverfasser: Jang, Na Young, Kim, Dan Hyo, Cho, Bong Jun, Choi, Eun Jung, Lee, Jong-Soo, Wu, Hong-Gyun, Chie, Eui Kyu, Kim, In Ah
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2015
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4355140/
https://ncbi.nlm.nih.gov/pubmed/25884663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-015-1090-7
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