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ISG15 silencing increases cisplatin resistance via activating p53-mediated cell DNA repair

Tumor cells frequently evolved resistance to cisplatin that greatly compromises the efficacy of chemotherapy. Identification of the mechanisms underlying drug resistance is important for developing new therapeutic approaches. ISG15 is found to be elevated in many human carcinomas and cancer cell lin...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Huo, Yi, Zong, Zhaoyun, Wang, Qingtao, Zhang, Zhenyu, Deng, Haiteng
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5746079/
https://ncbi.nlm.nih.gov/pubmed/29296177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.22488
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