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Exponential sensitivity of noise-driven switching in genetic networks

There is increasing experimental evidence that cells can utilize biochemical noise to switch probabilistically between distinct gene-expression states. In this paper, we demonstrate that such noise-driven switching is dominated by tails of probability distributions and is therefore exponentially sen...

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Veröffentlicht in:Phys Biol
Hauptverfasser: Mehta, Pankaj, Mukhopadhyay, Ranjan, Wingreen, Ned S
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5746052/
https://ncbi.nlm.nih.gov/pubmed/18560045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1088/1478-3975/5/2/026005
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