The Effects of Ex Vivo Administration of Granulocyte-Macrophage Colony-Stimulating Factor and Endotoxin on Cytokine Release of Whole Blood Are Determined by Priming Conditions

BACKGROUND: Lipopolysaccharide- (LPS-) induced tumour necrosis factor alpha (TNFα) secretion in critically ill patients can be considered as a measure of immune responsiveness. It can be enhanced by granulocyte-macrophage colony stimulating factor (GM-CSF). We investigated the effect of GM-CSF on ex...

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Detalhes bibliográficos
Publicado no:Biomed Res Int
Main Authors: Nierhaus, A., Linssen, J., Winkler, M. S., Frings, D. P., Kluge, S.
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5745690/
https://ncbi.nlm.nih.gov/pubmed/29387728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2017/9834512
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