The hematopoietic cytokine granulocyte-macrophage colony stimulating factor is important for cognitive functions

We recently reported expression of hematopoietic growth factor GM-CSF and its receptor (GM-CSFR) in CNS neurons. Here we evaluated this system in learning and memory formation using GM-CSF deficient mice. In complementation, GM-CSF signalling was manipulated specifically in adult murine hippocampus...

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Detalhes bibliográficos
Main Authors: Krieger, Markus, Both, Martin, Kranig, Simon A., Pitzer, Claudia, Klugmann, Matthias, Vogt, Gerhard, Draguhn, Andreas, Schneider, Armin
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3458247/
https://ncbi.nlm.nih.gov/pubmed/23019518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep00697
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