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Ectopic Phosphorylated Creb Marks Dedifferentiated Proximal Tubules in Cystic Kidney Disease

Ectopic cAMP signaling is pathologic in polycystic kidney disease; however, its spatiotemporal actions are unclear. We characterized the expression of phosphorylated Creb (p-Creb), a target and mediator of cAMP signaling, in developing and cystic kidney models. We also examined tubule-specific effec...

詳細記述

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書誌詳細
出版年:Am J Pathol
主要な著者: Puri, Pawan, Schaefer, Caitlin M., Bushnell, Daniel, Taglienti, Mary E., Kreidberg, Jordan A., Yoder, Bradley K., Bates, Carlton M.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Investigative Pathology 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5745541/
https://ncbi.nlm.nih.gov/pubmed/29107072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2017.09.015
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