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Loss of peri-Wolffian duct stromal Frs2α expression in mice leads to abnormal ureteric bud induction and vesicoureteral reflux

BACKGROUND: Fibroblast growth factor receptor 2 (Fgfr2) deletion from murine peri-Wolffian duct stroma (ST) results in aberrant ureteric bud induction, abnormal ureteral insertion into the bladder, and high rates of vesicoureteral reflux (VUR). It is unclear which receptor docking protein(s) is/are...

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Bibliografiske detaljer
Udgivet i:Pediatr Res
Main Authors: Narla, Deepti, Slagle, Stacey B., Schaefer, Caitlin M., Bushnell, Daniel S., Puri, Pawan, Bates, Carlton M.
Format: Artigo
Sprog:Inglês
Udgivet: 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5701656/
https://ncbi.nlm.nih.gov/pubmed/29135976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/pr.2017.175
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