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In vivo calcium imaging visualizes peripheral neuron sensitization in a surgical mouse model of osteoarthritis

OBJECTIVE: The purpose of this study was to develop a method for analyzing sensory neuron responses to mechanical stimuli in vivo, and to evaluate whether these neuronal responses change after destabilization of the medial meniscus (DMM). METHODS: DMM or sham surgery was performed in 10-week old mal...

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Detalhes bibliográficos
Publicado no:Arthritis Rheumatol
Main Authors: Miller, Rachel E., Kim, Yu Shin, Tran, Phuong B., Ishihara, Shingo, Dong, Xinzhong, Miller, Richard J., Malfait, Anne-Marie
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5745281/
https://ncbi.nlm.nih.gov/pubmed/28992367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.40342
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