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Damage-Associated Molecular Patterns Generated in Osteoarthritis Directly Excite Murine Nociceptive Neurons through Toll-like Receptor 4
OBJECTIVE: The aim of this study was to determine whether selected damage-associated molecular patterns (DAMPs) present in osteoarthritic (OA) joints excite nociceptors through toll-like receptor (TLR)-4. METHODS: The ability of S100A8 and α(2)-macroglobulin to excite nociceptors was determined by m...
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| Publicado no: | Arthritis Rheumatol |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4626273/ https://ncbi.nlm.nih.gov/pubmed/26245312 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.39291 |
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