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Functional Analysis of Corin Protein Domains Required for PCSK6-mediated Activation

Atrial natriuretic peptide (ANP) is a cardiac hormone essential for normal blood pressure and cardiac function. Corin is a transmembrane serine protease that activates ANP. Recently, we identified proprotein convertase subtilisin/kexin-6 (PCSK6), also called PACE4, as the long-sought corin activator...

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Bibliografiske detaljer
Udgivet i:Int J Biochem Cell Biol
Main Authors: Chen, Shenghan, Wang, Hao, Li, Heng, Zhang, Yue, Wu, Qingyu
Format: Artigo
Sprog:Inglês
Udgivet: 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5745258/
https://ncbi.nlm.nih.gov/pubmed/29180304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biocel.2017.11.010
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