PCSK6-mediated corin activation is essential for normal blood pressure

Hypertension is the most common cardiovascular disease, afflicting >30% of adults(1). The cause of hypertension in most individuals remains unknown(2,3), suggesting that additional contributing factors have yet to be discovered. Corin is a serine protease that activates the natriuretic peptides,...

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Détails bibliographiques
Publié dans:Nat Med
Auteurs principaux: Chen, Shenghan, Cao, Pengxiu, Dong, Ningzheng, Peng, Jianhao, Zhang, Chunyi, Wang, Hao, Zhou, Tiantian, Yang, Junhua, Zhang, Yue, Martelli, Elizabeth E, Prasad, Sathyamangla V Naga, Miller, Rachel E, Malfait, Anne-Marie, Zhou, Yiqing, Wu, Qingyu
Format: Artigo
Langue:Inglês
Publié: 2015
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4710517/
https://ncbi.nlm.nih.gov/pubmed/26259032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.3920
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