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Carboxylate Surrogates Enhance Antimycobacterial Activity of UDP-Galactopyranose Mutase Probes
Uridine diphosphate galactopyranose mutase (UGM also known as Glf) is a biosynthetic enzyme required for construction of the galactan, an essential mycobacterial cell envelope polysaccharide. Our group previously identified two distinct classes of UGM inhibitors; each possesses a carboxylate moiety...
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| Publicado no: | ACS Infect Dis |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5745143/ https://ncbi.nlm.nih.gov/pubmed/27626294 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsinfecdis.6b00021 |
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