Interleukins 12 and 15 induce cytotoxicity and early NK-cell differentiation in type 3 innate lymphoid cells

Type 3 innate lymphoid cells (ILC3s) fulfill protective functions at mucosal surfaces via cytokine production. Although their plasticity to become ILC1s, the innate counterparts of type 1 helper T cells, has been described previously, we report that they can differentiate into cytotoxic lymphocytes...

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Detalhes bibliográficos
Publicado no:Blood Adv
Main Authors: Raykova, Ana, Carrega, Paolo, Lehmann, Frank M., Ivanek, Robert, Landtwing, Vanessa, Quast, Isaak, Lünemann, Jan D., Finke, Daniela, Ferlazzo, Guido, Chijioke, Obinna, Münz, Christian
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2017
Assuntos:
Immunobiology and Immunotherapy
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5745129/
https://ncbi.nlm.nih.gov/pubmed/29296921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2017008839
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