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Maternal Gdf3 is an obligatory cofactor in Nodal signaling for embryonic axis formation in zebrafish

Zebrafish Gdf3 (Dvr1) is a member of the TGFβ superfamily of cell signaling ligands that includes Xenopus Vg1 and mammalian Gdf1/3. Surprisingly, engineered homozygous mutants in zebrafish have no apparent phenotype. Elimination of Gdf3 in oocytes of maternal-zygotic mutants results in embryonic let...

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Bibliografski detalji
Izdano u:eLife
Glavni autori: Bisgrove, Brent W, Su, Yi-Chu, Yost, H Joseph
Format: Artigo
Jezik:Inglês
Izdano: eLife Sciences Publications, Ltd 2017
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5745076/
https://ncbi.nlm.nih.gov/pubmed/29140249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.28534
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