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Maternal Gdf3 is an obligatory cofactor in Nodal signaling for embryonic axis formation in zebrafish
Zebrafish Gdf3 (Dvr1) is a member of the TGFβ superfamily of cell signaling ligands that includes Xenopus Vg1 and mammalian Gdf1/3. Surprisingly, engineered homozygous mutants in zebrafish have no apparent phenotype. Elimination of Gdf3 in oocytes of maternal-zygotic mutants results in embryonic let...
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| izdano v: | eLife |
|---|---|
| Main Authors: | , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
eLife Sciences Publications, Ltd
2017
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5745076/ https://ncbi.nlm.nih.gov/pubmed/29140249 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.28534 |
| Oznake: |
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