The natural compound Jatrophone interferes with Wnt/β-catenin signaling and inhibits proliferation and EMT in human triple-negative breast cancer

Metastatic breast cancer is the leading cause of worldwide cancer-related deaths among women. Triple negative breast cancers (TNBC) are highly metastatic and are devoid of estrogen receptor (ER), progesterone receptor (PR) and human epidermal growth factor receptor 2 (HER2) amplification. TNBCs are...

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Udgivet i:PLoS One
Main Authors: Fatima, Iram, El-Ayachi, Ikbale, Taotao, Ling, Lillo, M. Angeles, Krutilina, Raya, Seagroves, Tiffany N., Radaszkiewicz, Tomasz W., Hutnan, Miroslav, Bryja, Vitezslav, Krum, Susan A., Rivas, Fatima, Miranda-Carboni, Gustavo A.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2017
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5744972/
https://ncbi.nlm.nih.gov/pubmed/29281678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0189864
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