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Human Pegivirus (HPgV; formerly known as GBV-C) inhibits IL-12 dependent natural killer cell function

Human Pegivirus (HPgV, formally GB virus C) infects lymphocytes and NK cells in vivo, and infection is associated with reduced T cell and NK cell activation in HIV-infected individuals. The mechanism by which HPgV inhibits NK cell activation has not been assessed. Following IL-12 stimulation, IFNγ e...

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Detalhes bibliográficos
Publicado no:Virology
Main Authors: Chivero, Ernest T., Bhattarai, Nirjal, McLinden, James H., Xiang, Jinhua, Stapleton, Jack T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5744589/
https://ncbi.nlm.nih.gov/pubmed/26245365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2015.07.008
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