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Analysis of gene expression changes of drug metabolizing enzymes in the livers of F344 rats following oral treatment with kava extract()

The association of kava product use with liver-related risks has prompted regulatory action in many countries. We studied the changes in gene expression of drug metabolizing enzymes in the livers of Fischer 344 male rats administered kava extract by gavage for 14 weeks. Analysis of 22,226 genes reve...

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Detalhes bibliográficos
Publicado no:Food Chem Toxicol
Main Authors: Guo, Lei, Li, Quanzhen, Xia, Qingsu, Dial, Stacey, Chan, Po-Chuen, Fu, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5744584/
https://ncbi.nlm.nih.gov/pubmed/19100306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.fct.2008.11.037
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