Aminopurvalanol A, a Potent, Selective, and Cell Permeable Inhibitor of Cyclins/Cdk Complexes, Causes the Reduction of in Vitro Fertilizing Ability of Boar Spermatozoa, by Negatively Affecting the Capacitation-Dependent Actin Polymerization

The adoption of high-througput technologies demonstrated that in mature spermatozoa are present proteins that are thought to be not present or active in sperm cells, such as those involved in control of cell cycle. Here, by using an in silico approach based on the application of networks theory, we...

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Bibliographische Detailangaben
Veröffentlicht in:Front Physiol
Hauptverfasser: Bernabò, Nicola, Valbonetti, Luca, Greco, Luana, Capacchietti, Giulia, Ramal Sanchez, Marina, Palestini, Paola, Botto, Laura, Mattioli, Mauro, Barboni, Barbara
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2017
Schlagworte:
Physiology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5744433/
https://ncbi.nlm.nih.gov/pubmed/29312003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2017.01097
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