Aminopurvalanol A, a Potent, Selective, and Cell Permeable Inhibitor of Cyclins/Cdk Complexes, Causes the Reduction of in Vitro Fertilizing Ability of Boar Spermatozoa, by Negatively Affecting the Capacitation-Dependent Actin Polymerization

The adoption of high-througput technologies demonstrated that in mature spermatozoa are present proteins that are thought to be not present or active in sperm cells, such as those involved in control of cell cycle. Here, by using an in silico approach based on the application of networks theory, we...

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Dettagli Bibliografici
Pubblicato in:Front Physiol
Autori principali: Bernabò, Nicola, Valbonetti, Luca, Greco, Luana, Capacchietti, Giulia, Ramal Sanchez, Marina, Palestini, Paola, Botto, Laura, Mattioli, Mauro, Barboni, Barbara
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2017
Soggetti:
Physiology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5744433/
https://ncbi.nlm.nih.gov/pubmed/29312003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2017.01097
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